Abnormal paraclinical findings of the neonates with fever admitted to the neonantal ward of Amir-Kabir Hospital, Arak city in 2011

The vast clinical testing process often is performed to diagnose the origin of the fever. The aim of this study was to investigate the rate of abnormal paraclinical findings of the neonates with fever. This cross-sectional study was carried out on 109, randomly seleceted febrile neonates admittedta to Amir-Kahir Hospital 2010. Blood, Cerebro Spinal Fluid [CSF] and Urine samples were sent to laboratory and the results were analyzed by Chi-Square test, using SPSS software. Blood culture of 19 cases [17.43%] is positive. None of the CSF samples are gram positive and also show the sign of Meningitis. With regard to the high rate of positive blood culture, it seems that the use of blood culture in febrile neonates is important for diagnosis

cross-sectional study of the prevalence of coronary artery disease traditional risk factors in Yazd urban population, Yazd healthy heart project

Coronary artery disease [CAD] risk factors are increasing in developing countries. Previous studies have shown a high prevalence of CAD risk factors in Iran but Geographical prevalence is not uniform. The present study was performed to determine the prevalence of CAD risk factors among Yazd urban population. This cross- sectional study performed in 2004, comprised a total 2000 Yazd citizens [1000 males], and the corresponding data were recorded in questionnaires carrying 500 items. About 85% of Yazd citizens had at least one and 61.1% had at least two coronary artery risk factors. The following data in brackets refer to the males and females respectively. The present study showed obesity in 16.38% of Yazd citizens [9.2 and 24.2%]. The prevalence of hypercholesterolemia 12.1% [10.6 and 13.8%], dyslipidemia 58.5% [59% and 57.6%], high blood pressure 25.6% [27.5% and 23.5%], diabetes mellitus 11% [10.48% and 11.5%], impaired glucose tolerance test 8.5% [7.9% and 9.1%] and cigarette smoking 13.12% [24.45% and 0.5%]. Also 43.3% of men and 62.05% of women had excess weight. The prevalence of hypercholesterolemia, dyslipidemia, diabetes mellitus [DM], hypertention [HTN], and abdominal obesity increased significantly with age [P< 0.005]. The prevalence of obesity, abdominal obesity, hypercholesterolemia and DM were significantly higher in women. Yazd did not carry the highest levels of risk factors in Iran, but the present study showed excess weight, dyslipidemia and HTN were the most prevalent risk factors found in this region. Thus it is recommended to consider the preventive and therapeutic measures as the major health priorities in this area

Hypertension in Iranian urban population, epidemiology, awareness, treatment and control

To assess the epidemiological characteristics of hypertension patients in urban population of Yazd, A central city in Iran. This cross sectional study was conducted from 2005-2006 and carried out on population aging 20-74 years. It is a part of the phase I of Yazd healthy heart program that it is a community interventional study for prevention of cardiovascular disease. Data obtained from questionnaires were analyzed by SPSS version 13. P value less than 0.05 were considered significant level. This study comprised of 2000 participants that 847 [42.5%] were diagnosed as being hypertensive. After age adjustment, prevalence of hypertension was 25.6% [23.3% for women and 27.5% for men [P<0.001]. Age, Total cholesterol, LDL-cholesterol, triglyceride, fasting blood glucose, impaired glucose tolerance test, body mass index and waist were significantly higher in the hypertensive groups. 53.7% of hypertensive cases were aware of own condition, 45% were treated, and 33.9% of treated were controlled [30.7% and 35.4% in men and women respectively]. In other word, 24% of all hypertensives [aware or unaware about own blood pressure condition] were treated and only 8% of them were controlled. Men significantly had less awareness [P<0.001], lower tendency to take medication [P<0.001], and less were controlled [P=0.046]. We understand high prevalence, low awareness, treatment, and control of hypertension and higher prevalence of other traditional metabolic risk factors in these cases. It seems that urgent preventional studies should be conducted in this population

Effects of intracerebroventricular injection of histamine and H1, H2 receptor antagonists on electrocardiographic parameters in broiler chickens

The aim of this study was to assess the effects of exogenous histamine and H[1] and H[2] central receptors on electrocardiographic [ECG] parameters, heart rate and mean electrical axis in broiler chickens. For this purpose, Ross broiler chickens [750-800 g weight] received intracerebroventricularly [ICV] histamine. Moreover, to determine the receptors involved in histamine-induced alterations in ECG changes, H[1] and H[2] blockers were administered to histamine-treated chickens. All ECGs were standardized at 1 mV = 20 mm, with paper speed of 50 mm/sec. Leads I, II, III, aVR, aVL and aVF were recorded. Injection of histamine [200 and 300 micro g] decreased the duration of T wave and QRS complex and elevated the heart rate as compared to the control group [P<0.05]. Chlorpheniramine [100 micro g], an H[1] receptor antagonist, increased the duration rate of T wave and QRS complex and reduced the heart rate [P<0.05]. Cimetidine, an H[2] receptor antagonist [100 micro g] had no effect on ECG parameters. Pretreatment with chlorpheniramine [100 micro g] significantly attenuated histamine effects [200 micro g] on the duration of T wave, QRS complex and heart rate [P<0.05]. Mean electrical axis, calculated from leads II and III, did not differ between groups and it was between -93 [degree sign] and -99 [degree sign] in all chickens. In conclusion, exogenous histamine intracerebroventricularly results in sinusoidal tachycardia in broiler chickens and central H[1] receptors mediate the stimulatory effects of histamine on heart rate, but H[2] receptors had no role in this manner

[Using lms method in smoothing reference centile curves for lipid profile of iranian children and adolescents: a caspian study]

LMS is a general monitoring method for fitting smooth reference centile curves in medical sciences. They provide the distribution of a measurement as it changes according to some covariates like age or time. This method describes the distribution of changes by three parameters; Mean, Coefficient of variation and Cox-Box power [skewness]. Applying maximum penalized likelihood and spline function, the three curves are estimated and fitted and optimum smoothness is expressed by three curves. This study was conducted to provide the percentiles of lipid profile of Iranian children and adolescents by LMS. Smoothed reference centile curves of four groups of lipids [triglycerides, total-LDL- and HDL-cholesterol] were developed from the data of 4824 Iranian school students, aged 6-18 years, living in six cities [Tabriz, Rasht, Gorgan, Mashad, Yazd and Tehran-Firouzkouh] in Iran. Demographic and laboratory data were taken from the national study of the surveillance and prevention of non-communicable diseases from childhood [CASPIAN Study]. After data management, data of 4824 students were included in the statistical analysis, which was conducted by the modified LMS method proposed by Cole. The curves were developed with a degree of freedom of four to ten with some tools such as deviance, Q tests, and detrended Q-Q plot were used for monitoring goodness of fit models. All tools confirmed the model, and the LMS method was used as an appropriate method in smoothing reference centile. This method revealed the distributing features of variables serving as an objective tool to determine their relative importance. This study showed that the triglycerides level is higher and HDL-C level is lower in Iranian children and adolescents than their counterparts in Western countries. Future studies with larger sample size and with higher density at the end points and equal distribution of measurements in changing limits of covariates would hopefully reach more precise findings

[Prevalence of fungal and fungal like superficial infections in patients who refered to skin clinic of Arak university of medical science]

There are wide-ranging types of fungal infection and dependent on the site of involvement it is divided into five groups; superficial, cutaneous, mucocutaneous, subcutaneous and visceral infections. In humans cutaneous infection includes skin hair and nail disease. This study was done on 148 patients suspected to fungal infection. Samples were studied by direct smear and culture in S, SC and SCC culture media. From 148 patients referred to Medical laboratory, 90 patients had cutaneous infection [60.8%] among which 11 were infected with Tinea versicolor [12.23%], 4 with Candidiasis [4.44%], 73 with dermatophytosis [81.11%] and finally 2 patients with Demodecosis [2.22%]. In this study, dermatophytosis was the most prevalent infection and Tinea corporis had the most incidence among fungal infections. T. verocosome, a zoophyllic fungus, was the main culprit

Prevalence of traditional coronary artery disease risk factors in Yazd urban population: Yazd healthy heart project

Coronary artery disease [CAD] risk factors are increasing in developing countries. Previous studies have shown a high prevalence of CAD risk factors in Iran but geographical prevalence is not uniform. We performed this study to determine the prevalence of these risk factors in Yazd province, central Iran. In this cross-sectional study, a total of 2000 participants, 1000 men and 1000 women among Yazd citizens, were surveyed and data was recorded in a 500- item questionnaire. About 85% of Yazd citizens had at least one and 61.1% had at least two coronary artery disease risk factors. The present study showed that 16.38% of Yazd citizens were obese [9.2% in men and 24.2% in women], and 43.3% of men an d62.05% of women had excess weight. Prevalence of hypercholesterolemia was 12.1% [10.6 in men and 13.8% in women, respectively], dyslipidemia 58.5% [59% and 57.6%, respectively], high blood pressure [HTN] 25.6% [27.5% and 23.5%, respectively], diabetes mellitus [DM] 11% [10.48% and 11.5%, respectively], impaired glucose tolerance 8.5% [7.9 and 9.1%, respectively] and cigarette smoking 13.12% [24.45% and 0.55, respectively]. The prevalence of hypercholesterolemia, dyslipidemia, DM, HTN, and abdominal obesity increased significantly with age [p<0.005]. The prevalence of obesity, abdominal obesity, hypercholesterolemia and DM was significantly higher in women. Excess weight, dyslipidemia and HTN were the most prevalent risk factors in Yazd. Although Yazd did not have the highest levels of risk factors in Iran, but the findings showed that Yazd is one of the "at risk" cities with regard to prevalence of risk factors. Preventive and therapeutic programs should thus be considered as a major health priority in Yazd

Use of clonazepam and avoidance of sleep deprivation in the treatment of juvenile myoclonic epilepsy

Juvenile Myoclonic Epilepsy [J.M.E.] needs life-long anti-epileptic drug [AED] treatment. Of various drugs tried in this condition, valproate effectively treats all types of seizures seen in J.M.E. Among valproate side effects, neural tube defects [NTD] in the offspring, is a deterring factor in its use in childbearing period. To avoid NTD, most authorities advise on switching to AED drug before conception.As well, the effects of valproate on male fertility is feared of. Clonazepam controls only the myoclonic jerks, leaving the patients unprotected and susceptible to generalized seizures, which mostly occur in the morning after sleep deprivation. Sleep deprivation is the most prevalent precipitating factor for generalized seizures in these patients. Between Jan 2003 and April 2008, 15 newly diagnosed JME patients [9 girls, 6 boys], were given clonazepam [1.0-4.0 mg] at bedtime, and were compared to 16 patients on valproate treatment. All were advised to avoid sleep deprivation. This study showed, all patients in the clonazepam group, [100%] had full control of their myoclonic jerks; 4[26.6%] had breakthrough episodes of generalized seizures, provoked by sleep deprivation; the rest [11, 73.4%], were in full remission of their myoclonic and generalized seizures. In control group, 2 [12.5%], had episodes of breakthrough, sleep-deprived, generalized seizures; the rest [14, 87.5%] were in remission. Statistically, there was no significance between the results in both groups. Clonazepam side effects were limited to mild to moderate drowsiness in the morning, eliminated by giving the dose earlier at night. The study suggests that if J.M.E. patients avoid sleep deprivation, they can be treated with clonazepam alone to avoid side effects of valproate

Serum uric acid levels and its association with cardiovascular risk factors

Although the issue of hyperuricemia as a risk factor for cardiovascular diseases [CVD] has been disputed, several studies have shown an association between hyperuricemia and several CVD risk factors. The aim of this study was to assess distribution of uric acid level in Yazd City, center of Iran, and its association with CVD risk factors. From autumn 2004 to summer 2005, 2000 urban population of Yazd City, aging 20-74 years via clustering random sampling were enrolled in this cross sectional study. Serum uric acid level, systolic blood pressure [SBP], diastolic blood pressure [DBP] and waist/hip ratio were significantly higher in men than in women [P < 0.001],moreover, total cholesterol, HDL cholesterol and body mass index [BMI] were significantly higher in women [P < 0.001]. The prevalence of hyperuricemia and metabolic syndrome in men and women was [17.9%, 11.25% P = 0.001] and [11.87%, 19.32% P= 0.01], respectively. Hyperuricemia was more prevalent in metabolic syndrome and ischemic heart disease independent of age and sex. Significant correlations were found between serum uric acid and several components of the metabolic syndrome. Weight, waist circumstance, triglyceride level and DBP, were the major determinants of the variations in serum uric acid levels. This could be attributed to the insulin resistance status

Evaluation of liver volume and its megakaryocyte's population in NMRI mice fetus exposed to electromagnetic field

During the recent decades, a lot of studies were conducted to asses the effect of electromagnetic fields on fetal developmental disorders, sterility, and a variety of neoplasms. The aim of the present study was to determine the effect of low electromagnetic field [LEMF] on the liver's volume and the number of its megakaryocytes in NMRI mouse fetus. LEMF of 50 HZ frequency was used and 66 three month old NMRI mouse embryos were divided into 6 groups. The experimental groups were exposed to LEMF and then an embryo was randomly selected from each mother and its liver was extracted and fixed in formalin. Cell counting and volume evaluating were done by stereological methods and the data were analyzed. Although the number of liver megakaryocytes and the embryos weight in all experimental groups as compared to sham and control groups reduced but the differences were not significant. The results of this study revealed that in the pregnant mice exposed to LEMF, irrespective of the length of pregnancy, there was not a significant change in the liver volume and the number of liver's megakaryocytes in NMRI mouse fetus

[ effect of ethanol on growth and development of two-cell arrested mouse embryo]

Arresting in certain step of developing like two cell block, could be the reason of infertility in some couples. Evaluate the effect of ethanol on growth and development of mouse two-cell arrested embryo is aimed of this study. In this experimental study 4-6 weeks old female mice were coupled with male mice following superovulation. Positive vaginal plaque mice were killed 48 hour after HCG injection. Two cell embryos were collected in RPMI medium and cultured in M16 medium and divided in three groups. The 2[nd] and 3[rd] groups were exposed to 4[degree sign] [c] for 24 hour in order to delay and arrest for cleavage and developmental rate. The 2[nd] group [2[nd] control] were incubated immediately, while the 3[rd] group [experiment] were exposed to%0.1 Ethanole for 5 minutes and the 1[st] group [1[st]control] without any exposure to low temperature were incubated. The developmental rate of embryos exposed to low temperature [4[degree sign][c]] significantly decreased and induce, retardation and arrest [p=0.001]. There were not significant difference between the groups mean of cleavage rate, but the mean percent of degenerated embryos between groups have significant differences [p=0.045]. The mean percent of morulla were significantly different between groups [p=0.005]. The mean percent of blastocyst and hatched blastocyst after 120 hr evaluation have significant differences between others groups [p=0.014] [p=0.001]. Effect of%0.1 ethyl-alcohol on arrested two cell embryos can significantly increase the mean percent of morulla and development of blastocyst and hatching blastocyst stage in compare to control group, without any significant effect on cleavage rate

[Effective factors on writing of Persian and non Persian articles in Arak University of Medical Sciences faculty members' point of view in 2008]

Since of the importance of publishing medical articles in evaluation of faculty members' activity and ranking of universities, this study was designed investigate faculty members' opinion about intendancy in writing Persian and non Persian articles. This cross-sectional analytical study is carried out by census method. Data were gathered by a questionnaire which its validity and reliability were confirmed. Data was analyzed by ANOVA, T-test, Chi square and correlation coefficient. The most important barriers in academic members' intendancy to articles were too busy in education or clinical treatment with the mean of 4.28 +/- 1.06, lack of experienced persons fro writing non Persian articles as counselor with the mean of 3.98 +/- 1.00, lack of research teams with the man of 3.95 +/- 0.98, long time in proposal approval with the man of 3.96 +/- 1.02, lack of journal editorial board supporting in accepting of descriptive articles with the mean of 3.95 +/- 1.02 and long time from receiving articles until their approval and publishing with the mean of 3.95 +/- 1.07. By decreasing education hours, shortening the process of proposal approval, introducing expert persons in writing non Persian articles as counselor, shortening the process of evaluating and publishing or rejecting articles can increase academic members' tendency in writing articles

[ epidemiologic study of suicide attempt referred to hospitals of university of medical sciences in Markazi- province from 1384 to 1386]

Suicide is considered as an important cause of death in many societies. Although many factors involve, there are inadequate information in this field. The aim of this study was to determine related factor in individual who attempted suicide in Arak university of medical sciences [AUMS] hospitals in 1384 to 1386. This study was an observational study which was carried out in all attempted suicide in all hospitals affiliated to [AUMS] from 2004 to 2007 year. Demographic information, time of suicide, the number of suicide, the result of suicide, the form of suicide, emotion and history of suicide, material chronic and mental disorder were asked by completing a questionnaire and/or interview with individuals. Totally 4226 persons attempted to suicide during the 3 years. The mean age for attempted suicide was 24.95 +/- 9.72 years and for successful suicide was 29.79 +/- 13.72 years. Approximately 60% was female. Near 80% of female were lower than 30 years old. Around 60 percent had high school degree. Familial dispute was the major risk factor in attempting to suicide. 82.5% of persons used drug for their attempt to suicide. Nearly three percent of all suicide was successful. With regard to the lower rate of attempting suicide in this area, this important issue should be considered for health policy makers in Arak area

[Bed occupancy rate modeling in Shiraz hospitals]

The Bed Occupancy Rate [BOR] among Iranian hospitals was reported to be 57.4% in 2001 indicative of a significance difference with standard index of 75%. To evaluate the bed occupancy rate modeling in Shiraz hospitals. This was a cross-sectional study carried out on random samples from different hospitals in Shiraz during the first half of 2004. The Poisson models including the negative binomials and mixture Poisson were used for BOR modeling. Hierarchical mixture Poisson, negative binomial and hierarchical two-component normal distribution were applied for the role of each hospital ward. Our findings showed that the average BOR was 66.4% in Shiraz hospitals. Regarding the relative hemogenity in observation of BOR in different hospitals, the hierarchical mixture Poisson and negative binomial models failed to accurately explain this variable and it was the hierarchical mixture two-component normal model which gave an accurate explanation for BOR found in our study. In this model, one of the components indicates the BOR observation close to mean and the other represents the outlier observations. The hierarchical modeling in which a hospital ward acts as a random component was shown to lead to the highest value for BOR

[Clinical and paraclinical characteristics of hospitalized pa talents with congestive heart failure in Yazd [a survey of 258 patients]]

The Clinical and Paraclinical Characteristics of patients with congestive heart failure [CUF] have been described by a number of previous studies, but very little information is available on this issue in Iran. This study aimed to delineate the clinical and paraclinical characteristics of Iranian patients hospitalized with CHF. During an observational, analytical, descriptive, cross-sectional study, 258 consecutive patients were interviewed and examined at S hospitals in Yazd, Iran from January to December 1999.Questionnaire comprised of information regarding etiology, signs, symptoms, paraclinical data, etc. Results were analyzed by SPSS9.01 and EP16 programs using ANOVA, Chi-Square and f-TEST and reported as Mean +/- SD. The study population had a high mean age [67.59 +/- 0.73], 0.8% were less than 35 years old and 70.80% were older than 65 years. Mortality rate due to heart failure was 7.5%. Major causes of CHF were ischemia [65.1%]. valvular lesions [5.8%], cardiomyopathy [5%] and hypertensive heart diseases [4.6%]. Mean number of hospitalizations per year was 2.2 +/- 0.1, while mean hospitalization time was 7.25 +/- 3.8 days and mean cost was 1122439 +/- 89874.8 rials. Even though many background and aggravating factors of heart failure are preventable, this disease incurs a lot of expenditure on our country's health system. Therefore, there is a requirement for programming and research in the fields of education, treatment and prevention of this disease for all members of the community

[Prevalence of low birth weight and obesity and some concomitant factors in live offspring's in 2006 and compare with 2002 result's in Arak Talleghani hospital]

In this study prevalence of abnormal birth weight was estimated in live-born neonates in 2006 and compared with that of 2002 in Talleghani Hospital, Arak, Iran. Low birth weight [LBW] was classified weight of less than 2500 gram. The prevalence of LBW was explored base on sex, type of delivery and place of the living. The original supine length and weight data were calculated as body mass index [BMI] and compared with BMI at birth of Iran reference data. Overall prevalence of LBW was%9.1 that was less among boys in compare to girls. The LBW value in caesarean delivery was less than normal delivery. This index in mother lives in town was less than mothers who's living in rural area. Over two thirds of neonates had normal weight and more than 5% were overweight or obese. Girls BMI centiles was less than boys. In this study neonates were relatively free of overweight. The rate of neonatal underweight was striking. The LBW in 2006 was less than this value in 2002 in Talleghani Hospital; however, it was greater than the statistics in development country

[ comparison of statistical modeling strategies for analyzing length of stay in Shiraz education hospitals]

The modeling of inpatient length of stay [LOS] has important implications in various aspects of health care management, such as hospital management and planning, the management of health care resources and the performance in hospital care. For many health care management systems, it is important to develop a comprehensive analysis of LOS and to identify hospital- and patient-related characteristics influencing LOS variations. By targeting relevant factors, appropriate policies can be developed to manage the hospital care and the health care resources effectively. Except a specific and limited study, a few studies have carried out on LOS modeling in Iran. This study has been carried out to compare different models for explaining LOS. A sample of 3546 patients was selected using randomized clustered sampling scheme from different wards of Shiraz educational hospitals in 2005 and their hospitalization [LOS] rate registered as response variable and other demographic variables. Advance statistical models such as Poisson regression, ZTP, ZTNB and percentile regression were applied to analyze and modeling the data. Mean +/- S.D of LOS were calculated as 8.4 +/- 13.7days. Over-dispersion for LOS was observed. Therefore, negative binomial, gamma, zero truncated Poisson [ZTP], zero truncated negative binomial [ZTNB] and percentile regression were applied. The results showed that ZTNB is an efficient model for explaining LOS in Shiraz's hospitals. Given heterogeneity in LOS in different wards in Shiraz hospitals, negative binomial model explains adequately the LOS values. Also, percentile regression model seems appropriate for LOS which was applied to our data. Application of the cited models here to other hospitals scattered around the country is suggested

[ survey of age at natural menopause according to determinants factors in Arak city in 2007]

Menopause is a natural period of life. It means the permanent cessation of menstruation and the end of reproductive period which occurs between 45-52 years old. It also serves as an indicator of population health as the occurrence of menopause indicates the increased risk for the onset of several chronic diseases. In this study, the mean age of natural menopause among women in Arak [Central Iran] was investigated, considering their reproductive and socio-economic-demographic factors and their health behaviors. This study was an observational cross-sectional study on a population base, carried out in 2007 year. Interviews and questionnaires were used for gathering data from 458 women resident in Arak city, who had undergone a natural menopause. Sampling was multistaged using postal zones and selecting samples in each zone. Data was analyzed using variance analysis, multiple regression, T and correlation coefficient tests. Findings showed that the mean age of menopause in our sample was 48.2 +/- 2.34 years [95% CI: 47.98- 48.41] and its median was 49 years. The mean age of menopause in women who were never married was less than married women [P= 0.015]. Low income level [P= 0.003], having physical activity [P= 0.004], number of pregnancies [P<0.001], age of last pregnancy [P=0.026] and place of birth [P=0.003] were meaningfull factors in age of menopause. This phenomenon must be documented in Iran because of its strong link with mortality and morbidity of the growing number of women who are reaching advanced ages; whose one forth of life is after menopause. Therefore health education as the best way for changing their lifestyle is suggested

[Relation between admission blood glucose levels and in-hospital and one year mortality in non-diabetic acute myocardial infarction patients]

Several studies have evaluated the association of admission blood glucose levels and short and long term mortality after myocardial infarction and have had different results. The aim of this study was evaluation of association between admission blood glucose levels and in-hospital and one year mortality in non-diabetic patients with AMI. In this study, demographic, clinical and Para clinical data of 120 non-diabetic patients with AMI on admission was collected and analyzed. The patients were followed for one year. Blood glucose level >/= 140 mg/dl was defined as hyperglycemia. 78% of patients were men. The mean age and admission blood glucose level was 63 +/- 13 years and 146 +/- 76mg/dl, respectively. Death due to cardio vascular causes was seen in 20% of patients in hospital and 9.8% during the one year follow up. The mean admission blood glucose level in patients who died in hospital was significantly more than live patients and also had an influence on the in-hospital outcome. Every 100mg/dl increase in blood glucose level was associated with 11% increase in in-hospital mortality risk in non-diabetic patients. Our results demonstrate that admission blood glucose level is a good marker for diagnosing patients with worse prognosis after AMI. We suggest that later studies should focus on optimal control of hyperglycemia with insulin in patients with AMI

Length of hospital stay [LOS] modeling with mixture possion distribution

Modeling is one of the most fundamental methods of denoting statistical variables which by using it, we can found distribution of noted response variable. For analysis data same as length of hospital stay [LOS], we have not data normality and error variances homogeneity, so, we can use nonparametric methods or distribution correction likes logarithmic transferring for using parametric methods. According to experiences in this situation, considering mixture distributions approximately can improve goodness- of- fit distribution. The goal of this study was to introduce mixture Poisson modeling and using mixture Poisson regression models for explaining duration of patient hospitalization in hospital and gaining effective factors on this time of duration and also comparing these models with common regression models in these data. After interdicting mixture Poisson modeling and its regression, we applied these models for modeling LOS in two wards in Arak Vali-e-Asr hospital. Variables of age, marriage status, birth location and living location as independent variables and duration of hospitalization in hospital as countable response variable were considered and LOS was considered as response variable for application these models. The findings have shown that in base Log-likelihood value and more dispersion LOS data in the surgical ward mixture Poisson model was a suitable for explain LOS with the other variables and in internal ward the variation of hospitalization time is not great, so this model cannot describe this variable explanation. By consideration Log-likelihood value and variation of LOS in surgical ward, the Poisson mixture model is a good model for describing this variable. By using general models, the Log-likelihood value is more than mixture Poisson modeling and there are less significant factors in models. Application of these models in cases which the countable response variable has great variation, is recommended